790401 Engineering principles for continuous bioprocessing (in Eng.)

Art
Vorlesung und Übung
Semesterstunden
1
Vortragende/r (Mitwirkende/r)
Lingg, Nico , Satzer, Peter
Organisation
Angeboten im Semester
Sommersemester 2024
Unterrichts-/ Lehrsprachen
Englisch
Lehrinhalt

The lecture presents current trends in industry and academia for the continuous manufacturing of bioproducts, with a focus on biopharmaceutical products.

A special focus will be on the following unit operations:
Upstream
- Chemostat
- Turbidostat
- Perfusion culture
Downstream
- Simulated moving bed chromatography
- Periodic counter current chromatography
- Continuous counter current extraction

The special considerations that need to be taken into account for continuous operation will be discussed in contrast to batch operation. This lecture will expand the content of the lectures Up- and Downstream processing (791357), Bioprocess Engineering (791350) and Grundlagen Bioprozesstechnik (791120) to continuous manufacturing
Inhaltliche Voraussetzungen (erwartete Kenntnisse)

Basic knowledge of chemical engineering and bioprocesses. This includes basics in thermodynamics and basic knowledge for fermentation and cell biology.
Lehrziel

Students will be able to understand continuous processes and processes, will be able to describe them scientifically and from an engineering standpoint, and will be able to select the right methods for continuous production of biopharmaceuticals.
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