791333 Biology of aging (in Eng.)

Vorlesung und Seminar
Vortragende/r (Mitwirkende/r)
Grillari, Johannes , Schosserer, Markus
Institut für Biotechnologie
Angeboten im Semester
Sommersemester 2018
Unterrichts-/ Lehrsprachen


The elective course „ Biology of aging“ with seminar character for the Mater studies of Biotechnology (H418) and Food Science and Technology (H417) is allocated within biotechnology, food sciences and cell- and molecular biology.

In 6 connected moduls the students are going to learn about the principle of aging, different aging theories, the hallmarks of aging, the influence of stress and external environmental factors on the aging processes, as well as the influence of aging on fertility and tumorigenesis, evolutional aspects, different examples of aging processes in animals and cellular processes of aging.

Detailed course content:
1. What is aging?
2. Aging theories
3. Oxidative stress and calorie restriction
4. Aging and fertility
5. Evolutional aspects
6. Examples of aging processes:
6.1. Aging of yeast
6.2. Aging of worms: C. elegans
6.3. Aging of flys: D. melanogaster
6.4. Rodents
6.5. The cell culture model of replicative senescence
7. The hallmarks of aging
8. Premature aging syndroms
9. Tumorigenesis and aging

Inhaltliche Voraussetzungen (erwartete Kenntnisse)

Basic knowledge of cell- and molecular biology is highly recommended!


After successful completion of this elective course students will have a broad overview of the interdisciplinary field of biogerontology and the latest developments in the field. They can outline the most important concepts and hallmarks of aging and know how they are currently applied to increase life quality of aged persons. Students are able to explain the molecular and cellular processes of aging and they can give examples of aging processes in organs and different organisms (microorganims, animals and humans). Furthermore they can point out the influence of aging on fertility and tumorigenesis and summarize premature aging syndroms.
Noch mehr Informationen zur Lehrveranstaltung, wie Termine oder Informationen zu Prüfungen, usw. finden Sie auf der Lehrveranstaltungsseite in BOKUonline.