802302 Prokaryotic glycoconjugates and disease


Type
Lecture
Semester hours
2
Lecturer (assistant)
Schäffer, Christina
Organisation
BIMat
Offered in
Sommersemester 2019
Languages of instruction
Englisch

Content

The lecture provides an overview on the architecture, occurrence, biosynthesis, molecular biology, and analysis of bacterial glycoconjugates, as well as their impact of infectious diseases pinpointing strategies for therapeutic intervention

The lecture includes the following topics:

Bacterial glycoconjugates: S-layer glycoproteins of bacteria and archaea, peptidoglycan/pseudomurein, lipopolysaccharides, teichoic/ teichuronic/ lipoteichoic acids, glycosylated cell surface appendages, other bacterial glycoconjugates

Glycobiology & infectious diseases: biofilm, quorum sensing, OMVs

Therapeutic strategies: e.g., glycoconjugate vaccines

.

Previous knowledge expected

general Microbiology, biochemistry, molecular biology.

Objective (expected results of study and acquired competences)

After successful completion of this lecture, students have acquired a deep understanding of bacterial glycobiology comprising theoretical background andapplied aspects for interlinking glycobiology and infectious diseases with application potential in a biomedical context.

Students are able
… to assess the biological relevance of different bacterial glycoconjugates
… to design rational approaches for influencing glycobiology-based biological phenomena
… to apply their knowledge in the way of looking at scientific challenges in glycobiology

Students have acquired theoretical competence in glycoconjugate analysis and data interpretation as well as in glycosylation engineering.
You can find more details like the schedule or information about exams on the course-page in BOKUonline.